Generic & Class
|
Brand & Company
|
Strength
|
Formulations†
|
Usual Dose
|
|
ANALGESIC + BARBITURATE
|
|||||
acetaminophen
|
DOLGIC PLUS
(Victory Pharma) |
750mg
|
Rx
|
tabs
|
Children: not recommended.
Adults: 1 tab every 4 hrs; max 5 tabs/day. |
butalbital
|
50mg
|
||||
caffeine
|
40mg
|
||||
acetaminophen
|
ESGIC PLUS
(Mikart) |
500mg
|
Rx
|
scored tabs; caps
|
Children: not recommended.
Adults: 1 cap or tab every 4 hours as needed. |
butalbital
|
50mg
|
||||
caffeine
|
40mg
|
||||
acetaminophen
|
FIORICET
(Watson) |
325mg
|
Rx
|
tabs
|
Children: not recommended.
Adults: 1–2 tabs or caps every 4 hours as needed; max 6/day. |
butalbital
|
50mg
|
||||
caffeine
|
40mg
|
||||
acetaminophen
|
PHRENILIN
(Valeant) |
325mg
|
Rx
|
tabs
|
|
butalbital
|
50mg
|
||||
ANALGESIC + BARBITURATE + OPIOID
|
|||||
acetaminophen
|
FIORICET w. CODEINE
(Watson) |
325mg
|
CIII
|
caps
|
Children: not recommended.
Adults: 1–2 tabs or caps every 4 hours as needed; max 6/day. |
butalbital
|
50mg
|
||||
caffeine
|
40mg
|
||||
codeine phosphate
|
30mg
|
||||
ANALGESIC + SALICYLATE
|
|||||
acetaminophen
|
BAYER MIGRAINE FORMULA
(Bayer Consumer) |
250mg
|
OTC
|
caplets
|
Children: not recommended.
Adults: 2 caplets with a glass of water. Max 2 caplets/24 hours. |
aspirin
|
250mg
|
||||
caffeine
|
65mg
|
||||
acetaminophen
|
EXCEDRIN MIGRAINE
(Novartis Consumer Health) |
250mg
|
OTC
|
tabs
|
Children: not recommended.
Adults: Take with full glass of water. ≥18yrs: 2 tabs every 6 hours as needed; max 8 tabs/day for 2 days. |
aspirin
|
250mg
|
||||
caffeine
|
65mg
|
||||
ANALGESIC + SYMPATHOMIMETIC
|
|||||
acetaminophen
|
MIGRATEN
(Azur Pharma) |
325mg
|
Rx
|
caps
|
Children: not recommended.
Adults: Tension: 1–2 caps every 4 hours; max 8 caps/day. Migraine: 2 caps at once, then 1 cap every hour until relieved; max 5 caps/12 hours. |
caffeine
|
100mg
|
||||
isometheptene mucate
|
65mg
|
||||
BARBITURATE + SALICYLATE
|
|||||
aspirin
|
FIORINAL
(Watson) |
325mg
|
CIII
|
tabs; caps
|
Children: not recommended.
Adults: 1–2 tabs or caps every 4 hours as needed; max 6/day. |
butalbital
|
50mg
|
||||
caffeine
|
40mg
|
||||
BARBITURATE + SALICYLATE + OPIOID
|
|||||
aspirin
|
FIORINAL w. CODEINE
(Watson) |
325mg
|
CIII
|
caps
|
Children: not recommended.
Adults: 1–2 tabs or caps every 4 hours as needed; max 6/day. |
butalbital
|
50mg
|
||||
caffeine
|
40mg
|
||||
codeine phosphate
|
30mg
|
||||
ERGOT ALKALOID
|
|||||
dihydroergotamine mesylate
|
D.H.E. 45
(Valeant) |
1mg/mL
|
Rx
|
IM, IV, or SC inj
|
Children: not recommended.
Adults: 1mL IV at 1 hour intervals; max 2 doses/day. Or, 1mL IM or SC at 1-hour intervals; max 3 doses/day. For all: max 6 doses/week. Do not use chronically. |
MIGRANAL**
(Valeant) |
4mg/mL
|
Rx
|
nasal spray
|
Children: not recommended.
Adults: 1 spray in each nostril, repeat 15 minutes later; max 6 sprays/24 hrs and 8 sprays/wk. |
|
ergotamine tartrate
|
(various)
|
1mg
|
Rx
|
tabs
|
Children: not recommended.
Adults: 2 tablets at onset of attack, then 1 tablet every ½ hour if needed; max 6 tabs/attack, 10 tabs/week. |
caffeine
|
100mg
|
||||
ergotamine tartrate
|
(various)
|
2mg
|
Rx
|
rectal supp
|
Children: not recommended.
Adults: 1 supp rectally at onset of attack, then 1 supp after 1 hour if needed; max 2 supps/attack, 5 supps/week. |
caffeine
|
100mg
|
||||
NON-STEROIDAL ANTI-INFLAMMATORY (NSAID)
|
|||||
diclofenac potassium
|
CAMBIA
(Nautilus) |
50mg
|
Rx
|
Buffered pwd for oral soln
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: mix 1 packet (50mg) with 30–60mL of water only and drink immediately. |
ibuprofen
|
ADVIL MIGRAINE
(Pfizer Consumer Healthcare) |
200mg
|
OTC
|
liquid-filled caps
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: Usually 400mg once daily. |
MOTRIN MIGRAINE PAIN
(McNeil Consumer & Specialty) |
200mg
|
OTC
|
caplets
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: Usually 200mg–400mg once daily. |
|
SELECTIVE 5-HT1B/1D RECEPTOR AGONIST
|
|||||
almotriptan (malate)
|
AXERT
(Janssen) |
6.25mg, 12.5mg
|
Rx
|
tabs
|
Adults and Children: <12yrs: not recommended. ≥12yrs: 6.25mg or 12.5mg single
dose; may repeat once after 2 hours; max 25mg/24hrs. Hepatic or severe
renal impairment (CrCl 10–30mL/minute) or concomitant potent CYP3A4
inhibitors (eg, ketoconazole): initially 6.25mg once; max
12.5mg/24 hours. The safety of treating an average of more than 4
headaches over 30 days is not established.
|
eletriptan HBr
|
RELPAX
(Pfizer) |
20mg, 40mg
|
Rx
|
tabs
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 20mg or 40mg once. Reevaluate if no response. May repeat once after 2 hours; max 80mg/day. The safety of treating an average of more than 3 headaches in a 30-day period has not been established. |
frovatriptan (as succinate)
|
FROVA
(Endo) |
2.5mg
|
Rx
|
tabs
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 2.5mg with fluids; may repeat once after 2 hours; max 7.5mg/24 hours. Reevaluate if no response after 1st dose. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. |
naratriptan HCl
|
AMERGE
(GlaxoSmithKline) |
1mg, 2.5mg
|
Rx
|
tabs
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 1mg or 2.5mg with fluids; may repeat once after 4 hours; max 5mg/24 hours. The safety of treating, on average, more than 4 headaches in a 30-day period has not been established. Mild-to-moderate renal or hepatic impairment: consider lower initial dose; max 2.5mg/24 hours. |
rizatriptan (as benzoate)
|
MAXALT
(Merck) |
5mg, 10mg
|
Rx
|
tabs
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: Initially 5 or 10mg; may repeat after 2 hrs; max 30mg/day. Concomitant propranolol: use 5mg dose; max 3 doses/day. The safety of treating, on average, more than 4 headaches in a 30-day period has not been established. |
MAXALT-MLT*
(Merck) |
5mg, 10mg
|
Rx
|
ODT
|
||
sumatriptan (as succinate)
|
ALSUMA
(Meridian Med Tech) |
6mg/0.5mL
|
Rx
|
soln for SC inj
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: one (6mg) dose SC to the lateral thigh or upper arm only. Reevaluate if no response. May repeat after 1 hour; max two (6mg) doses in 24 hours. |
IMITREX INJECTION
(GlaxoSmithKline) |
4mg/0.5mL, 6mg/0.5mL
|
Rx
|
SC inj
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 6mg SC (may start at lower dose if 6mg not tolerated). Reevaluate if no response. May repeat after 1 hour; max two 6mg doses in 24 hours. |
|
IMITREX NASAL SPRAY
(GlaxoSmithKline) |
5mg per spray, 20mg per spray
|
Rx
|
nasal spray
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 5mg, 10mg, or 20mg once. Reevaluate if no response. May repeat once after 2hrs; max 40mg/day. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. |
|
IMITREX TABLETS
(GlaxoSmithKline) |
25mg, 50mg, 100mg
|
Rx
|
tabs
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 25–100mg once, swallow whole with fluids as soon as possible after migraine onset; may repeat dose at intervals of at least 2hrs, max 200mg/day; or single-dose tablets up to 100mg/day if injection has been used. Hepatic dysfunction: max 50mg/dose. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. |
|
SUMAVEL DOSEPRO
(Zogenix) |
6mg/0.5mL
|
Rx
|
soln for SC inj
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: one DosePro (6mg) SC to the abdomen or thigh only. Reevaluate if no response. May repeat after 1 hour; max two DosePro (6mg) doses in 24 hours. |
|
zolmitriptan
|
ZOMIG
(Impax) |
2.5mg+, 5mg
|
Rx
|
tabs
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: Initially 2.5mg or lower once. If headache returns, may repeat after 2 hrs; max 10mg/day. Reevaluate if no response after 1st dose. The safety of treating an average of more than 3 headaches in a 30-day period has not been established. Hepatic impairment: use low dose. ZMT: dissolve on tongue and swallow without water. |
ZOMIG NASAL SPRAY
(Impax) |
5mg per spray
|
Rx
|
nasal spray
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: 5mg once. If headache returns, may repeat once after 2 hrs; max 10mg/day. Reevaluate if no response after 1st dose. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. Hepatic impairment: use low dose oral form. |
|
ZOMIG-ZMT*
(Impax) |
2.5mg, 5mg
|
Rx
|
ODT
|
Children: <18yrs: not recommended.
Adults: ≥18yrs: Initially 2.5mg or lower once. If headache returns, may repeat after 2 hrs; max 10mg/day. Reevaluate if no response after 1st dose. The safety of treating an average of more than 3 headaches in a 30-day period has not been established. Hepatic impairment: use low dose. ZMT: dissolve on tongue and swallow without water. |
|
SELECTIVE 5-HT1B/1D RECEPTOR AGONIST + NON-STEROIDAL
ANTI-INFLAMMATORY (NSAID)
|
|||||
sumatriptan (as succinate)
|
TREXIMET
(GlaxoSmithKline) |
85mg
|
Rx
|
tabs
|
Children: not recommended.
Adults: Swallow whole. 1 tab once; may repeat once after 2 hours; max 2 tabs/day. The safety of treating an average of more than 5 migraines in a 30-day period has not been established. |
naproxen sodium
|
500mg
|
||||
NOTES
|
|||||
* = contains phenylalanine
** = contains caffeine + = scored tablets
† tabs = tablets; caps = capsules;
inj = injection; ODT = orally disintegrating tablets;
soln = solution; supp = suppositories;
IM = intramuscular; IV = intravenous;
SC = subcutaneous
Not an inclusive list. Please see
drug monograph .
|
|||||
Migraine and Headache Treatments
Posts
