Biostatistics & Research Methodology--PharmD Notes

  1    Research Methodology--Introduction
   a) Types of clinical study designs:
  Case studies, observational studies, interventional studies
   b)Designing the methodology
  c) Sample size determination and Power of a study
      Determination of sample size for simple comparativeexperiments, determination of sample size to obtain a confidence interval ofspecified width, power of a study.
             d)   Report writing and presentation of data
              Sampling Theory and Methods--PPT
2    Biostatistics
2.1 a) Introduction        
 c) Measures describing the central tendency distributions- average, median, mode
 d)Measurement of the spread of data-range, variation of mean, standard deviation, variance, coefficient of variation, standard error of mean.

      2.3 Basics of testing hypothesis
a) Null hypothesis, level of significance, power of test, P value, statistical estimation of confidence intervals.
b)   Level of significance (Parametric data)- students t test (paired and unpaired), chi Square test, Analysis of Variance (one-way and two-way)
c)   Level of significance (Non-parametric data)- Sign test, Wilcoxan’s signed rank test, Wilcoxan rank sum test, Mann Whitney U test, Kruskal-Wall is test (one way ANOVA)
      Pearsonn’s and Spearmann’s correlation and correlation co-efficient.
e)   Introduction to statistical software: SPSS      Epi Info        SAS

2.4 Statistical methods in epidemiology   

Computer System in Hospital Pharmacy